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Isothermal Titration Calorimeter



  • Isothermal Titration Calorimetry (ITC) is a powerful analytical tool which measures the binding affinity and thermodynamics between any two biomolecules.
  • ITC directly measures the heat released or absorbed during molecular binding.
  • Measurement of this heat enables direct accurate determination of these thermodynamic parameters in a single experiment: binding affinity (KD), stoichiometry (n), enthalpy (ΔH) and entropy (ΔS)
  • Wide range of applications including characterization of molecular interactions with small molecules, proteins, antibodies, nucleic acids, lipids, metal ions, etc., as well as enzyme kinetics & inhibitor studies.
  • Small volumes: 200 μl of sample per experiment.
  • The ITC200 is operated by skilled personnel only. Analysis can be done by the user.
  • Visit the Microcal website for more information about ITC.


Contact details:

Sylva Schwager
Email: sylva.schwager@uct.ac.za

Tel. 021 406-6469

Department of Integrative Biomedical Sciences
IDM-UCT Medical School
Wernher&Beit North, N3.05
Anzio Rd


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